(734) 369-8782
3280 Washtenaw Ave., Suite B.
Ann Arbor, MI 48104
M-F 10-6, Sat 10-2, Sun CLOSED
(734) 369-8782 | 3280 Washtenaw Ave., Suite B. Ann Arbor, MI 48104 | M-F 9-6, Sat 10-2 Refill my Rx Contact us

What is Low-Dose Naltrexone?

Naltrexone belongs to a class of drugs called opioid antagonists. It was approved by the FDA in 1984, at the 50 mg dose. At this approved dose, it works by binding to opioid receptors in the brain and blocking opioids from binding to these receptors. It basically prevents the feelings of well-being that people with an opioid addiction get when they take this pain medication. Because of its mechanism of action at this dosage, Naltrexone is used for the treatment of opioid and alcohol abuse.

How Does Low-Dose Naltrexone Work?

In 1985, Bernard Bihari, MD, a physician in New York City, discovered the effects of using a lower dose of naltrexone (3-4.5 mg) in the body’s immune system. Recent trials also show the efficacy of Low-Dose Naltrexone (LDN) for the treatment of immune-related conditions, including multiple sclerosis.

The mechanism of action of LDN is not fully understood, but researchers believe that, when it is administered at bedtime, the body responds to it by increasing endogenous endorphins and enkephalin leading to a boost in the immune system.

middle aged woman smiling benefiting from low-dose naltrexone
older woman washing vegetables at the sink benefiting from low-dose naltrexone

Uses for Low-Dose Naltrexone

Because of its believed mechanism of action, LDN is used for many of the conditions listed below.

Questions? Contact us for more information.

  • Fibromyalgia
  • Autism spectrum
  • Celiac disease
  • Crohn’s disease
  • Multiple Sclerosis
  • Lupus
  • Rheumatoid arthritis
  • Alzheimer’s disease
  • Parkinson’s disease

Getting started at Clark Professional
Pharmacy is as easy as 1-2-3

Talk to your healthcare provider: get a compounded prescription from your doctor
Fax or bring in your prescription: have your prescription faxed over or just bring it into Clark Pharmacy in Ann Arbor, Michigan
Pick up your medications: your order can be shipped to you or picked up from Clark Pharmacy in Ann Arbor Michigan

Questions? We're here to help.

Contact Us Today

3280 Washtenaw Ave., Suite B.
Ann Arbor, MI 48104

(734) 369-8782

(734) 585-5184


Mon - Fri: 9 am - 6 pm
Sat: 10 am - 2 pm